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OcuPhase® is a sterile eye-drop formulation offering two proven lubricants – hydroxypropylmethylcellulose and glycerin – that are approved by the FDA for ophthalmic use.
Suggested Use: For general preventive use, the recommended amount is 1–2 drops daily. Those with eye problems may want to use 2 drops twice daily or as needed.
OcuPhase also contains 1% N-acetylcarnosine, a naturally occurring antioxidant and antiglycating agent that helps protect the active ingredients from glycation. OcuPhase also contains ophthalmic lubricating agents to combat “dry eye” and other forms of eye irritation. Each box contains two vials containing five milliliters each.
Each package contains two resealable vials containing a total of about 200 drops, which allows for only a small amount of product to be exposed to oxygen at a time. Unopened vials can be stored in the refrigerator to extend shelf life.
Active Ingredients: Glycerin (lubricant) 1.0%, hydroxypropylmethylcellulose (lubricant) 0.15%
Inactive Ingredients: Sterile water (ophthalmic grade isotonic solution, pH 6.3 to 6.4), N-acetylcarnosine (NAC) 1.0%, buffered with boric acid, citric acid, and potassium bicarbonate, and, as a preservative, purified benzyl alcohol.
Good nutrition is a key element of preventing numerous age-related issues, including the health of our eyes. As we age our eyes become more susceptible to a host of challenges that can lead to irritation, discomfort and changes to vision. Colors may be dulled or distorted, and there may be an annoying halo of light around bright objects, causing a glare effect.
Applying lubricating eye drops several times a day can help to alleviate discomfort. Additionally, a number of nutrients have been shown to benefit eye health and good vision. One of these, carnosine, is a dipeptide consisting of two amino acids (alanine and histidine) connected by a chemical bond. Based on research performed mainly by Russian scientists, it is believed that carnosine's antioxidant properties support healthy vision by inhibiting a chemical process called glycation.
Glycation leads to deleterious chemical complexes called AGEs (advanced glycation end products) that result from common but undesirable reactions between blood sugars, such as glucose, and proteins in many parts of our bodies, including the lenses of our eyes. The sugar-protein complexes become chemically cross-linked and degrade cellular functions. The aptly named AGEs are thought to be an important factor in the aging process.
Carnosine eye drops have been shown to aid in delaying vision senescence in humans by restoring the natural structure of proteins in the lens.
N-acetylcarnosine (NAC), like its parent compound, carnosine, occurs naturally throughout the human body. Both compounds are found primarily in the heart and skeletal muscles (the word carnosine is derived from the Latin word for flesh) and in the brain. Carnosine was discovered in 1900 in Russia, and it is in Russia that most of the recent research on the N-acetylcarnosine derivative has been carried out. Research with N-acetylcarnosine, as with carnosine, demonstrates that it is effective for improving transmissivity of light through the lens.
The structural difference between NAC and carnosine is that one hydrogen atom in carnosine replaces an acetyl group (CH3CO-), and this substitution occurs at a nitrogen atom. An important chemical difference between carnosine and N-acetylcarnosine is that carnosine is relatively insoluble in lipids (fats and fatty compounds), whereas N-acetylcarnosine is relatively soluble in lipids (as well as in water).
This means that N-acetylcarnosine may pass through the lipid membranes of the corneal and lens cells more easily than carnosine, and may thereby gain access more readily to the cells’ interior, which is primarily aqueous. There, the N-acetylcarnosine is gradually broken down to carnosine (and, perhaps, to histidine), which then exerts its beneficial effects.
Carnosine and N-acetylcarnosine eye drops appear to be a safe, effective means for supporting eye health, comfort and quality of vision in aging humans.
I just had to write to thank you for your carnosine eye drops. My mother, Chanahhei, is 79 years old and has suffered from vision problems many years. Her doctors wanted her to go into hospital for surgery but I don't trust them and hospitals much after our previous experiences with them so she hadn't gone. Then a couple of months ago a good friend of mine told me about your eye drops and that they could help her without the need for surgery. This sounded too good to be true but I decided to get them for her as I feel anything is preferable to surgery and she is my mum and I'll do anything for her.
I started putting the drops into her eyes for her every day, once in the morning, once in the afternoon, and then again in the evening.
Already, after just seven weeks of using them the white film has cleared from her eyes and there is now just a very small patch left in the corners. She can now see my finger again which she couldn't before and everyday like clockwork she reminds me that it's time for her drops. Thank you so much for such a wonderful product and I am now telling everyone about them and how great they are.
Mary & Chanahhei – Middlesex, UK
I just wanted you to know that the improvement in my vision is amazing. I had gotten to the point where I could no longer drive due to haziness from my vision, and now I feel very secure and am able to see almost as well as before. I also have not noticed any kind of side effects.
I just wanted to tell you how happy I am and that I am definitely recommending carnosine eye drops to all my friends with similar problems! If you need me for any referrals or statistics I would be happy to help! Please keep on with the great work!
I want to tell you about my experiences with the eye-drops. At first I didn't think there were any real differences, but I persisted in using the drops twice a day in the affected eye. Now after about 3-months I believe that there are significant changes to my vision.
It's been a fairly gradual thing, which may explain why I didn't appreciate any changes early on, but now it's obvious to me that my eyesight has improved. The changes are slower than I anticipated, but I for one am sold on the drops!
My mother and I have used the drops for some 4 to 5 months with excellent results. My mothers vision has cleared completely. I use the computer for many hours a day and suffered from tired and sore eyes. I put 1 drop in each eye first thing in the morning and the result is that I can now work without any discomfort. If I've had a particularly grueling day with a lot of driving in the dark I use another drop -– the results are immediate, they are impressive and they make my life much more comfortable.
If you suffer from sore or tired eyes, have a vision issue or are of an age when vision issues are likely to start (+50) then I recommend carnosine eye drops. The drops are economical to use and they DO WORK. Try them!!
Roger Cooke - Wakefield, UK
What is the recommended daily use of OcuPhase?
For general preventive use, the recommended amount is 1–2 drops daily. Those with eye problems may want to use 2 drops twice daily or as needed.
Can children use OcuPhase?
OcuPhase eyedrops are not recommended for children under the age of 12 years.
What if I experience any discomfort when using OcuPhase eyedrops?
If the eye tissue becomes more inflamed, red, irritated or uncomfortable after using this product, immediately discontinue the use of product and consult an eye physician if necessary.