Nutritional
Support for Relief from Peri-and Postmenopausal Symptoms
FemmePhase® is a new dietary supplement
that alleviates three of the major concerns that women have
when passing through menopause:
FemmePhase works by improving the function
of the glands and organs that control ovulation and menstruation
and by enhancing blood circulation.
Menopause marks the end of a woman’s menstruation and
her reproductive lifespan. It usually occurs between the ages
of 35 and 55. The hormonal changes that occur before and after
the cessation of ovulation and menstruation are thought to
reflect the aging process. Imbalances in the hormonal interplay
between the hypothalamus, the pituitary, and the ovaries cause
the many, varied symptoms that make up the menopausal syndrome.
These include irregular cycles, missed periods, hot flashes,
night sweats, palpitations, emotional fragility and depression,
headaches, memory loss, insomnia, loss of libido, vaginal
dryness, dry skin.
However, these same alterations in hormonal
chemistry are also felt to contribute to the major disorders
of aging for women – the atherosclerosis underlying
heart disease and stroke and the loss of bone mass leading
to osteoporosis and increased rates of bone fracture.
When passing through menopause, the ovaries
lose ability to produce estrogen and progesterone. The hypothalamus
tries to adjust for this loss by temporarily increasing levels
of follicle stimulating hormone [FSH] and luteinizing hormone
[LH], hormones that stimulate estrogen production. Also, the
adrenal glands and fat cells take over some level of estrogen
production. Many women pass through this period of adjustment
with few symptoms.
However, menopausal syndrome is epidemic
among American women because a number of contributing factors
keep the varied regulating hormones in imbalance:
- Stress from overwork
- Poor nutrition
- Lack of exercise
- Excessive intake of synthetic hormones
from animal foods
- Excessive exposure to chemical pollutants
- Eating disorders including anorexia and
bulimia
- Surgical removal of the uterus and ovaries
A number of studies indicate that FemmePhase is a valuable
supplement for the varied causes and symptoms of menopause,
including the broader imbalances that accompany aging.
In a study carried out at the Shanghai Center for Modern Traditional
Chinese Medicine Technology, 50 women with menopausal syndrome
were treated with FemmePhase. Their ages ranged from: 44 -
60 years. Their symptoms included various levels of anxiety,
emotional instability, headache and dizziness, tinnitus and
blockage of hearing, oppressive sensations of the chest, palpitations,
restlessness, anger, hot flashes, spontaneous sweating, aching
of the legs and low back, uncontrollable crying, and depression.
After taking FemmePhase (shortest administration
period, 1 month; longest, 3 months), 30 patients experienced
complete relief of symptoms, 13 experienced marked improvement,
and three some improvement. Of the patients with complete
relief of symptoms, none of the symptoms had returned six
months after discontinuation of treatment.
In a second study the FemmePhase formula
was evaluated in both men (68) and women (82) as a treatment
for neurasthenia. Neurasthenia is a disorder of nervous exhaustion
that shares many symptoms with menopausal syndrome, including
depression, irritability, lack of focus, memory loss, insomnia
and dream-disturbed sleep, dizziness and headache, limb pain,
and various autonomic nervous system disorders. After three
months of administration of the formula, 75 cases had fully
recovered, 48 patients experienced marked improvement, 16
were noted as improved and 11 cases gained no improvement.
A third study looked at the use of FemmePhase
in treating angioneurotic headaches. Angioneurotic headaches
are characterized by spasms of the blood vessels resulting
from disturbances of the vasomotor system. Of the 84 patients
in the study, 68 were female and 16 male ranging in age from
17 to 52 years. They experienced 1+ headache per month with
an average duration of the condition of 2.5 years. The headaches
were experienced as frontal, bilateral, vertex, or occipital
with throbbing, distending, pounding, or stabbing pain. Accompanying
symptoms included light-headedness, irritability, insomnia,
irregular menses in the female patients, and depression.
After a course of treatment with the formula,
54 cases experienced recovery in which all symptoms disappeared,
rheoencephalogram readings improved indicating normalization
of blood vessel tension, and there was no recurrence of headache
one year later. 25 patients experienced improvement in which
headaches and other symptoms disappeared and headache returned
three months after treatment. Only 5 cases experienced no
improvement.
According to Subhuti Dharmananda in his paper The Endocrine
Effect of Chinese Medicine, “Chinese herbs act
by stimulating the production of hormones, altering the condition
of hormone receptors or changing the rate of catabolism of
hormones, rather than by providing the hormones or hormone
analogs that function the same as hormones.”
In the case of FemmePhase, pharmacodynamic
studies in animals have revealed that the formula is capable
of markedly increasing the estrogen receptor levels of the
pituitary gland, hypothalamus, and ovaries in aged rats.
While the ability of FemmePhase to increase
glandular estrogen receptor levels is a likely contributor
to its efficacy, the formula is also affecting the autonomic
nervous system. Hot flashes, the most common menopausal symptom,
are due to instability of the brain’s relay system,
its neurotransmitters, which are affected by the lowered levels
of estrogen in the blood stream as menopause progresses. This
instability affects our autonomic nervous system (ANS). It
is the ANS that is responsible for our body’s thermostatic
control, contraction and dilation of the blood vessels and
skin pores, perspiration, and other automatic physiological
responses of our body.
The apparent ability of FemmePhase to reduce
hot flashes and angioneurotic headaches indicates that it
has a positive impact on neurotransmitter function in regulating
the hypothalamic, pituitary, ovarian homeostat.
FemmePhase has been found to improve the blood circulation
of the heart and brain by promoting vessel dilation and inhibiting
the clumping of red blood corpuscles, thus increasing blood
flow.
The formula was originally designed to treat
the symptoms that follow cerebrovascular accident or stroke.
In a study of 98 post stroke cases, including 56 men and 42
women, 72 patients showed marked recovery after a course of
treatment with the herbal formula.
Numerous animal studies indicate that the
nutrient combination in the formula improved microcirculation
in the capillaries, inhibited formation of thromboxane A2
to aid in prevention of blood clots, and reversed platelet
aggregation and elevations of blood and plasma viscosity.
Other animal studies have found that this formula stimulates
a protective mechanism against heart muscle cell deterioration.
All of the benefits of improved blood flow
including improved vessel dilation and lowered viscosity should
be of great benefit to women following menopause who regularly
ingest the ingredients in FemmePhase. This improved blood
flow will also have an additional benefit in preserving the
function of the organs and glands that determine healthy endocrine
function as women age.
Improved blood flow can also make a positive contribution
to the prevention of bone loss in postmenopausal women. After
menopause, bone loss accelerates for 3-5 years, at a rate
of from 1.5% to 5% per year. Bone loss then continues at a
lower level of around 1% to 1.5% loss per year on average.
Six of the ten herbs in FemmePhase are commonly
used in China in the treatment and reversal of Avascular Necrosis
of The Femoral Head. In this severe disorder, the head of
the femur at the hip collapses from a lack of blood flow and
that destroys bone tissue. It is commonly a result of chronic
use of corticosteroid therapy.
The herbs in FemmePhase are central to the
restoration of blood flow and bone mass density in this condition.
Angelica sinensis and cordyceps are thought to be the chief
herbs that assist in this disorder and are central herbs in
the FemmePhase formula. While it diminishes symptoms of menopausal
syndrome, FemmePhase should also provide women with protection
against osteoporosis. [A separate formula from Tango Advanced
Nutrition, OsteoPhase, regulates calcium homeostasis in a
manner that is directly beneficial for osteoporosis.]
Clinical trials indicate that FemmePhase is capable of effecting
regulatory changes of the endocrine and circulatory systems
such that many of the signs of aging, including those of menopause
are either ameliorated or even alleviated.
The formula can be taken by women at the
earliest signs of changes that indicate the approach of menopause
to ease them through the transition with minimal symptoms.
After menopause, FemmePhase can be taken regularly to continue
to assist in maintaining optimal endocrine, circulatory and
skeletal health.
Menopausal syndrome with the following symptoms: hot flashes
and night sweats, dryness of the skin, poor memory and concentration,
depression, tearfulness, anxiety, insomnia, and loss of libido.
2 tablets, 2 times daily. For persistent insomnia, take an
additional 2 capsules at bedtime, or follow practitioner’s
advice. Symptom alleviation is usually evident after 2 or
4 bottles, after which FemmePhase can be taken at a rate of
1 tablet, 2 times daily for health maintenance.
Through animal studies, FemmePhase was not found to induce
any toxicologic reactions. Side effects and other adverse
reactions have not been detected during human clinical studies.
Pharmacologic Actions of FemmePhase Ingredients
Ingredients
Traditional actions and indications: Nourishes the blood,
promotes the flow of blood, regulates the menses, relieves
pain, moistens the intestines and relieves constipation.
Clinical effects: Improves microcirculation
and vessel dilation, thus increasing blood flow rate and preventing
hemagglutination. Helps control serum cholesterol. Has calming,
pain relieving, and anti-inflammatory effects.
Clinical effects: Has vessel dilation and anti-platelet agglutination
effects. Major constituent is capable of penetrating the blood-brain
barrier and being stored in the brain stem, thus improving
the dilation-contraction function of the blood vessels of
the brain. Has sedating and pain relieving effects; alleviates
spasms; has antihypertensive effect.
Clinical effects: Improves microcirculation and thus blood
flow, promotes the establishment of collateral blood vessels.
Promotes tissue repair and regeneration, inhibits overproliferation
of fibrous cells. Has sedating effect.
Clinical effects: Contains more ginsenosides than ginseng;
alleviates fatigue, has an overall strengthening effect. Strengthens
the heart; reduces myocardial oxygen consumption; dilates
the vessels; reduces artery pressure; raises coronary blood
flow.
Clinical effects: Improves bone marrow function; accelerates
red blood cell production, has excitatory effect on smooth
muscle of the intestines, blood vessels, and bronchi, dilates
the coronary artery, relieves angina pectoris, improves low
cardiac output.
Clinical effects: Has mild antiperistalsis effect on the stomach
and intestines. Has sedating effect; has antihypertensive
effect; promotes urination.
Clinical effects: Raises blood pressure during which blood
flow through the coronary artery, brain, and kidneys is increased,
alleviates allergic reactions by inhibiting the release of
anaphylaxin.
Clinical effects: Increases immunity, lowers total serum lipid
levels, thus alleviating the formation of atheromatous lesions,
and has sedating and sleep-promoting effects.
Clinical effects: Reduces menstrual pain, abdominal pain,
trauma pain, moistens the intestines to lessen constipation.
Clinical effects: Stops cough, promotes the discharge of puss,
soothes sore throat, and directs the effects of other herbs
to the upper body.
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